This position is funded by the Comunidad de Madrid through the 2020 Call for the Youth guarantee (Ref. PEJ-2020-AI/BIO-17904).

The work activity of the Research Assistant will be integrated in the research project: “The Anti-aging properties of venom-derived compounds”-          

Main functions to carry out:

• Screening of an Animal Venom-Biobank in senescent, cancer and non-transformed cell lines.
• Molecular and metabolic profiling of the compound-candidates.
• Assays for determining cell proliferation, apoptosis, mitochondrial membrane potential, reactive oxygen species and cell cycle by flow cytometry.
• Protein and RNA extractions to perform afterwards western blotting and real time PCR to reveal the effect of our candidate compounds at a protein and transcriptional level in cells.
• Biochemical analysis of tissue and tumour samples obtained in vivo from xenograft tumor and mouse models of senescence and cancer treated with venom-derived compounds.

Education requirements: BSc or MSc in Biology and Life Sciences-related fields

Experience requirements: Highly motivated Research Assistant with demonstrated expertise in cell, biotechnology and molecular biology. Specifically, the candidate should have experience in:
- Cell culture & husbandry
- High throughput screening

- Purification of DNA & RNA extractions

- Transfection of DNA/RNA vectors
- Western blotting
- Quantitative Real Time PCR
Other merits to evaluate: Expertise in the generation of xenograft tumors & in experimental mouse models of cancer, use of FACS or cell metabolism assays would be appreciated.
Skills: The Translational Venomics Lab has an international profile with interactions with overseas research groups in Europe, America and Australia. Hence, the successful candidate should have an excellent level of English and be able to work in a multidisciplinary collaborative and interactive environment within the IMDEAFood institute and another research centres

Los candidatos serán seleccionados en base al perfil descrito en Requisitos por un Comité de Selección compuesto por personal científico de IMDEA Food Institute. En el proceso podrían participar expertos ad hoc.

La selección de las candidaturas que mejor se adapten a los requisitos establecidos, pasarán a la segunda fase de selección consistente en una entrevista personal.

La entrevista personal consistirá en la realización de una entrevista presencial o por videoconferencia que versará únicamente sobre los méritos alegados por los candidatos en la fase de concurso y se dirigirá a valorar la adecuación del candidato al puesto. La entrevista tendrá una duración máxima de 45 minutos.

Contract: Temporary full-time training* contract with trial period established by law.

               *Requirements: Degree obtained in the last 5 years. Not having had a training employment contract previously 

Duration: This position is from 01/10/2021, max. untill 24/04/2023.

Dedication: Full time (37,5 hours per week) with morning and afternoon shift from Monday to Friday. Incompatible with any other employment contract.

Annual gross salary: 18.563 euro

The financial contribution of the Comunidad de Madrid, including Social Security, is 22.500 € per year.

Sede del Instituto IMDEA Alimentación, Madrid (SPAIN)